Publications (2011)
1. Papers from Biobank Japan
Genome-wide association study of epirubicin-inducedleukopenia in Japanese patients.
Srinivasan Y, Sasa M, Honda J, Takahashi A, Uno S, Kamatani N, Kubo M,
Nakamura Y, Zembutsu H.
Pharmacogenet Genomics. 2011 Sep;21(9):552-8.
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Doi S, Fujita K, Miyatake A, Enomoto T, Miyagawa T, Adachi M, Tanaka H, Niimi A, Matsumoto H, Ito I, Masuko H, Sakamoto T, Hizawa N, Taniguchi M, Lima JJ, Irvin CG, Peters SP, Himes BE, Litonjua AA, Tantisira KG, Weiss ST, Kamatani N, Nakamura Y, Tamari M.
Nat Genet. 2011 Jul 31;43(9):893-6.
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
Mbarek H, Ochi H, Urabe Y, Kumar V, Kubo M, Hosono N, Takahashi A, Kamatani Y, Miki D, Abe H, Tsunoda T, Kamatani N, Chayama K, Nakamura Y, Matsuda K.
Hum Mol Genet. 2011 Jul 27. [Epub ahead of print]
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
Miki D, Ochi H, Hayes CN, Abe H, Yoshima T, Aikata H, Ikeda K, Kumada H, Toyota J, Morizono T, Tsunoda T, Kubo M, Nakamura Y, Kamatani N, Chayama K.
Nat Genet. 2011 Jul 3. doi:10.1038/ng.876. [Epub ahead of print]
Identification of nine novel Loci associated with white blood cell subtypes in a Japanese population.
Okada Y, Hirota T, Kamatani Y, Takahashi A, Ohmiya H, Kumasaka N, Higasa K, Yamaguchi-Kabata Y, Hosono N, Nalls MA, Chen MH, van Rooij FJ, Smith AV, Tanaka T, Couper DJ, Zakai NA, Ferrucci L, Longo DL, Hernandez DG, Witteman JC, Harris TB, O'Donnell CJ, Ganesh SK, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Tamari M, Yamamoto K, Kamatani N.
PLoS Genet. 2011 Jun;7(6):e1002067.
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y; Human Disease Genomics Working Group; RA Clinical and Genetic Study Consortium, Okada Y, Nakamura Y, Yamamoto K, Melchers I, Lathrop M, Mimori T, Matsuda F.
Hum Mol Genet. 2011 Jul 1;20(13):2680-5. Epub 2011 Apr 19.
A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
Iida A, Takahashi A, Kubo M, Saito S, Hosono N, Ohnishi Y, Kiyotani K, Mushiroda T, Nakajima M, Ozaki K, Tanaka T, Tsunoda T, Oshima S, Sano M, Kamei T, Tokuda T, Aoki M, Hasegawa K, Mizoguchi K, Morita M, Takahashi Y, Katsuno M, Atsuta N, Watanabe H, Tanaka F, Kaji R, Nakano I, Kamatani N, Tsuji S, Sobue G, Nakamura Y, Ikegawa S.
Hum Mol Genet. 2011 Jun 10. [Epub ahead of print]
Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes.
Maeda S, Koya D, Araki S, Babazono T, Umezono T, Toyoda M, Kawai K, Imanishi M, Uzu T, Suzuki D, Maegawa H, Kashiwagi A, Iwamoto Y, Nakamura Y.
Clin Exp Nephrol. 2011 Jun;15(3):381-90. Epub 2011 Feb 18.
Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population.
Cui R, Okada Y, Jang SG, Ku JL, Park JG, Kamatani Y, Hosono N, Tsunoda T, Kumar V, Tanikawa C, Kamatani N, Yamada R, Kubo M, Nakamura Y, Matsuda K.
Gut. 2011 Jun;60(6):799-805. Epub 2011 Jan 17.
Common Variants in a Novel Gene, FONG on Chromosome 2q33.1 Confer Risk of Osteoporosis in Japanese.
Kou I, Takahashi A, Urano T, Fukui N, Ito H, Ozaki K, Tanaka T, Hosoi T, Shiraki M, Inoue S, Nakamura Y, Kamatani N, Kubo M, Mori S, Ikegawa S.
PLoS One. 2011 May 6;6(5):e19641.
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
Kumar V, Kato N, Urabe Y, Takahashi A, Muroyama R, Hosono N, Otsuka M, Tateishi R, Omata M, Nakagawa H, Koike K, Kamatani N, Kubo M, Nakamura Y, Matsuda K.
Nat Genet. 2011 May;43(5):455-8. Epub 2011 Apr 17.
A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
Cha PC, Takahashi A, Hosono N, Low SK, Kamatani N, Kubo M, Nakamura Y.
Nat Genet. 2011 May;43(5):447-50. Epub 2011 Apr 3.
Common variation in GPC5 is associated with acquired nephrotic syndrome.
Okamoto K, Tokunaga K, Doi K, Fujita T, Suzuki H, Katoh T, Watanabe T, Nishida N, Mabuchi A, Takahashi A, Kubo M, Maeda S, Nakamura Y, Noiri E.
Nat Genet. 2011 May;43(5):459-63. Epub 2011 Mar 27.
Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
Kumar V, Matsuo K, Takahashi A, Hosono N, Tsunoda T, Kamatani N, Kong SY, Nakagawa H, Cui R, Tanikawa C, Seto M, Morishima Y, Kubo M, Nakamura Y, Matsuda K.
J Hum Genet. 2011 Apr 7. [Epub ahead of print]
Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
Iida A, Takahashi A, Deng M, Zhang Y, Wang J, Atsuta N, Tanaka F, Kamei T, Sano M, Oshima S, Tokuda T, Morita M, Akimoto C, Nakajima M, Kubo M, Kamatani N, Nakano I, Sobue G, Nakamura Y, Fan D, Ikegawa S.
Neurobiol Aging. 2011 Apr;32(4):757.e13-4. Epub 2011 Feb 3.
Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population.
Low SK, Zembutsu H, Takahashi A, Kamatani N, Cha PC, Hosono N, Kubo M, Matsuda K, Nakamura Y.
J Hum Genet. 2011 Mar;56(3):211-6. Epub 2011 Jan 13.
Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
Okada Y, Takahashi A, Ohmiya H, Kumasaka N, Kamatani Y, Hosono N, Tsunoda T, Matsuda K, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N.
Hum Mol Genet. 2011 Mar 15;20(6):1224-31. .Epub 2010 Dec 31.
Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
Ozeki T, Mushiroda T, Yowang A, Takahashi A, Kubo M, Shirakata Y, Ikezawa Z, Iijima M, Shiohara T, Hashimoto K, Kamatani N, Nakamura Y.
Hum Mol Genet.2011 Mar 1;20(5):1034-41. Epub 2010 Dec 10.
PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
Kochi Y, Thabet MM, Suzuki A, Okada Y, Daha NA, Toes RE, Huizinga TW, Myouzen K, Kubo M, Yamada R, Nakamura Y, Yamamoto K.
Ann Rheum Dis. 2011 Mar;70(3):512-5. . Epub 2010 Nov 9.
Optineurin mutations in Japanese amyotrophic lateral sclerosis.
Iida A, Hosono N, Sano M, Kamei T, Oshima S, Tokuda T, Kubo M, Nakamura Y, Ikegawa S.
J Neurol Neurosurg Psychiatry. 2011 Jan 8. [Epub ahead of print]
SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Aoki A, Ozaki K, Sato H, Takahashi A, Kubo M, Sakata Y, Onouchi Y, Kawaguchi T, Lin TH, Takano H, Yasutake M, Hsu PC, Ikegawa S, Kamatani N, Tsunoda T, Juo SH, Hori M, Komuro I, Mizuno K, Nakamura Y, Tanaka T.
J Hum Genet. 2011 Jan;56(1):47-51. Epub 2010 Nov 25.
Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
Chung S, Nakagawa H, Uemura M, Piao L, Ashikawa K, Hosono N, Takata R, Akamatsu S, Kawaguchi T, Morizono T, Tsunoda T, Daigo Y, Matsuda K, Kamatani N, Nakamura Y, Kubo M.
Cancer Sci. 2011 Jan;102(1):245-52. doi: 10.1111/j.1349-7006.2010.01737.x. Epub 2010 Sep 28.
2. Papers related to personalized medicine
Evaluation of CYP2D6 and Efficacy of Tamoxifen and Raloxifene in Women Treated for Breast Cancer Chemoprevention: Results from the NSABP P-1 and P-2 Clinical Trials.
Goetz MP, Schaid DJ, Wickerham DL, Sagfren S, Mushiroda T, Kubo M, Batzler A, Costantino JP, Vogel VG, Paik S, Carlson EE, Flockhart DA, Wolmark N, Nakamura Y, Weinshilboum RM, Ingle JN, Ames M.
Clin Cancer Res. 2011 Aug 31. [Epub ahead of print]
Genome-wide Association Study Identifies Variations in 6p21.3 Associated With Nevirapine-Induced Rash.
Chantarangsu S, Mushiroda T, Mahasirimongkol S, Kiertiburanakul S, Sungkanuparph S, Manosuthi W, Tantisiriwat W, Charoenyingwattana A, Sura T, Takahashi A, Kubo M, Kamatani N, Chantratita W, Nakamura Y.
Clin Infect Dis. 2011 Aug;53(4):341-8.
Genome-wide association study on bipolar disorder in the Bulgarian population.
Yosifova A, Mushiroda T, Kubo M, Takahashi A, Kamatani Y, Kamatani N, Stoianov D, Vazharova R, Karachanak S, Zaharieva I, Dimova I, Hadjidekova S, Milanova V, Madjirova N, Gerdjikov I, Tolev T, Poryazova N, O'Donovan MC, Owen MJ, Kirov G, Toncheva D, Nakamura Y.
Genes Brain Behav. 2011 Jul 19. doi:10.1111/j.1601-183X.2011.00721.x. [Epub ahead of print]
Multiple loci are associated with white blood cell phenotypes.
Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Völzke H, Gouskova NA, Biffi A, Döring A, Völker U, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N, Stumvoll M, Tönjes A, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin J, Pistis G, Uitterlinden AG, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK.
PLoS Genet. 2011 Jun;7(6):e1002113.
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
Reiner AP, Lettre G, Nalls MA, Ganesh SK, Mathias R, Austin MA, Dean E, Arepalli S, Britton A, Chen Z, Couper D, Curb JD, Eaton CB, Fornage M, Grant SF, Harris TB, Hernandez D, Kamatini N, Keating BJ, Kubo M, LaCroix A, Lange LA, Liu S, Lohman K, Meng Y, Mohler ER 3rd, Musani S, Nakamura Y, O'Donnell CJ, Okada Y, Palmer CD, Papanicolaou GJ, Patel KV, Singleton AB, Takahashi A, Tang H, Taylor HA Jr, Taylor K, Thomson C, Yanek LR, Yang L, Ziv E, Zonderman AB, Folsom AR, Evans MK, Liu Y, Becker DM, Snively BM, Wilson JG.
PLoS Genet. 2011 Jun;7(6):e1002108.
The HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis but Reduces Risk for Crohn's Disease.
Okada Y, Yamazaki K, Umeno J, Takahashi A, Kumasaka N, Ashikawa K, Aoi T, Takazoe M, Matsui T, Hirano A, Matsumoto T, Kamatani N, Nakamura Y, Yamamoto K, Kubo M.
Gastroenterology. 2011 Jun 20.[Epub ahead of print]
IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
Abe H, Hayes CN, Ochi H, Maekawa T, Tsuge M, Miki D, Mitsui F, Hiraga N, Imamura M, Takahashi S, Kubo M, Nakamura Y, Chayama K.
J Hepatol. 2011 Jun;54(6):1094-101. Epub 2011 Feb 4.
Personalizing carbamazepine therapy.
Mushiroda T, Nakamura Y.
Genome Med. 2011 May 30;3(5):28. [Epub ahead of print]
For what am I participating? The need for communication after receiving consent from biobanking project participants: experience in Japan.
Watanabe M, Inoue Y, Chang C, Hong H, Kobayashi I, Suzuki S, Muto K.
J Hum Genet. 2011 May;56(5):358-63. Epub 2011 Mar 10.
IL-28B predicts response to chronic hepatitis C therapy -fine-mapping and replication study in Asian populations.
Ochi H, Maekawa T, Abe H, Hayashida Y, Nakano R, Imamura M, Hiraga N, Kawakami Y, Aimitsu S, Kao JH, Kubo M, Tsunoda T, Kumada H, Nakamura Y, Hayes CN, Chayama K.
J Gen Virol. 2011 May;92(Pt 5):1071-81. Epub 2011 Jan 12.
Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
Kawaoka T, Hayes CN, Ohishi W, Ochi H, Maekawa T, Abe H, Tsuge M, Mitsui F, Hiraga N, Imamura M, Takahashi S, Kubo M, Tsunoda T, Nakamura Y, Kumada H, Chayama K.
J Hepatol. 2011 Mar;54(3):408-14. Epub 2010 Sep 19.
Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
Umeno J, Asano K, Matsushita T, Matsumoto T, Kiyohara Y, Iida M, Nakamura Y, Kamatani N, Kubo M.
Inflamm Bowel Dis. 2011 Feb 23. doi: 10.1002/ibd.21651. [Epub ahead of print]
Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?
Zembutsu H, Sasa M, Kiyotani K, Mushiroda T, Nakamura Y.
Expert Rev Anticancer Ther. 2011 Feb;11(2):185-93.
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Suzuki F, Suzuki Y, Akuta N, Sezaki H, Hirakawa M, Kawamura Y, Hosaka T, Kobayashi M, Saito S, Arase Y, Ikeda K, Kobayashi M, Chayama K, Kamatani N, Nakamura Y, Miyakawa Y, Kumada H.
Hepatology. 2011 Feb;53(2):415-21. doi: 10.1002/hep.24058. Epub 2011 Jan 18
