Publications (2010)
1. Papers from Biobank Japan
Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
Cha PC, Mushiroda T, Takahashi A, Kubo M, Minami S, Kamatani N, Nakamura Y.
Hum Mol Genet. 2010 Dec 1;19(23):4735-44. Epub 2010 Sep 10.
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa
H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jørgensen T, Lauritzen T, Sandbæk A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H,
So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T.
Nat Genet. 2010 Oct;42(10):864-8. Epub 2010 Sep 5.
Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
Miki D, Kubo M, Takahashi A, Yoon KA, Kim J, Lee GK, Zo JI, Lee JS, Hosono N, Morizono T, Tsunoda T, Kamatani N, Chayama K, Takahashi T, Inazawa J, Nakamura Y, Daigo Y.
Nat Genet. 2010 Oct;42(10):893-6. Epub 2010 Sep 26.
A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression.
Akamatsu S,
Takata R, Ashikawa K, Hosono N, Kamatani N, Fujioka T, Ogawa O, Kubo M, Nakamura Y, Nakagawa H
Hum Mol Genet. 2010 Aug 27. [Epub ahead of print]
A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
Nakashima M, Chung S, Takahashi A, Kamatani N, Kawaguchi T, Tsunoda T, Hosono N, Kubo M, Nakamura Y & Zembutsu H.
Nat Genet. 2010 Aug 15. [Epub ahead of print]
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
Takata R, Akamatsu S, Kubo M, Takahashi A, Hosono N, Kawaguchi T, Tsunoda T, Inazawa J, Kamatani N, Ogawa O, Fujioka T, Nakamura Y, Nakagawa H.
Nat Genet. 2010 Aug 1. [Epub ahead of print]
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Uno S, Zembutsu H, Hirasawa A, Takahashi A, Kubo M, Akahane T, Aoki D, Kamatani N, Hirata K, Nakamura Y.
Nat Genet. 2010 Aug;42(8):707-10. Epub 2010 Jul 4.
Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes.
Kumasaka N, Yamaguchi-Kabata Y, Takahashi A, Kubo M, Nakamura Y, Kamatani N
J Hum Genet. 2010 Aug;55(8):525-33. Epub 2010 Jun 17.
Making a haplotype catalog with estimated frequencies based on SNP homozygotes
Yamaguchi-Kabata Y, Tsunoda T, Takahashi A, Hosono N, Kubo M, Nakamura Y, Kamatani N
J Hum Genet. 2010 Aug;55(8):500-6. Epub 2010 May 20
Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
Iida A, Kamei T, Sano M, Oshima S, Tokuda T, Nakamura Y, Ikegawa S
Neurobiol Aging. 2010 Jul 30. [Epub ahead of print]
Genome-wide association study of pancreatic cancer in Japanese population.
Low SK, Kuchiba A, Zembutsu H, Saito A, Takahashi A, Kubo M, Daigo Y, Kamatani N, Chiku S, Totsuka H, Ohnami S,Hirose H, Shimada K, Okusaka T, Yoshida T, Nakamura Y, Sakamoto H
PLoS One. 2010 Jul 29;5(7):e11824
Identification of Evidence Suggestive of an Association with Peripheral Arterial Disease at the OSBPL10 Locus by Genome-Wide Investigation in the Japanese Population.
Koriyama H, Nakagami H, Katsuya T, Sugimoto K, Yamashita H, Takami Y, Maeda S, Kubo M, Takahashi A, Nakamura Y, Ogihara T, Rakugi H, Kaneda Y, Morishita R
J Atheroscler Thromb. 2010 Jul 2. [Epub ahead of print]
Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
Matsushita T, Umeno J, Hirakawa Y, Yonemoto K, Ashikawa K, Amitani H, Ninomiya T, Hata J, Doi Y, Kitazono T, Iida M, Nakamura Y, Kiyohara Y, Kubo M
J Hum Genet. 2010 Jul;55(7):473-6. Epub 2010 May 7
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
Okada Y, Kamatani Y, Takahashi A, Matsuda K, Hosono N, Ohmiya H, Daigo Y, Yamamoto K, Kubo M, Nakamura Y,Kamatani N
Hum Mol Genet. 2010 Jun 1;19(11):2303-12. Epub 2010 Feb 26
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility
Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, Yamazaki K, Hosono N, Myouzen K, Tsunoda T, Kamatani N, Furuichi T, Ikegawa S, Ohmura K, Mimori T, Matsuda F, Iwamoto T, Momohara S, Yamanaka H, Yamada R, Kubo M, Nakamura Y, Yamamoto K.
Nature Genetics. 2010 Jun;42(6):515-9. Epub 2010 May 9.
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
Okada Y, Kamatani Y, Takahashi A, Matsuda K, Hosono N, Ohmiya H, Daigo Y, Yamamoto K, Kubo M, Nakamura Y,Kamatani N
Hum Mol Genet. 2010 May 15;19(10):2079-85. Epub 2010 Feb 18
Genome-wide association study of intracranial aneurysm identifies three new risk loci.
Yasuno K, Bilguvar K, Bijlenga P, Low SK, Krischek B, Auburger G, Simon M, Krex D, Arlier Z, Nayak N, Ruigrok YM,Niemelä M, Tajima A, von und zu Fraunberg M, Dóczi T, Wirjatijasa F, Hata A, Blasco J, Oszvald A, Kasuya H, Zilani G,Schoch B, Singh P, Stüer C, Risselada R, Beck J, Sola T, Ricciardi F, Aromaa A, Illig T, Schreiber S, van Duijn CM, van den Berg LH, Perret C, Proust C, Roder C, Ozturk AK, Gaál E, Berg D, Geisen C, Friedrich CM, Summers P, Frangi AF,State MW, Wichmann HE, Breteler MM, Wijmenga C, Mane S, Peltonen L, Elio V, Sturkenboom MC, Lawford P, Byrne J,Macho J, Sandalcioglu EI, Meyer B, Raabe A, Steinmetz H, Rüfenacht D, Jääskeläinen JE, Hernesniemi J, Rinkel GJ,Zembutsu H, Inoue I, Palotie A, Cambien F, Nakamura Y, Lifton RP, Günel M
Nat Genet. 2010 May;42(5):420-5. Epub 2010 Apr 4
The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
Kumasaka N, Nakamura Y, Kamatani N
PLoS One. 2010 Apr 27;5(4):e10207
New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
Nakajima M, Takahashi A, Kou I, Rodriguez-Fontenla C, Gomez-Reino JJ, Furuichi T, Dai J, Sudo A, Uchida A, Fukui N, Kubo M, Kamatani N, Tsunoda T, Malizos KN, Tsezou A, Gonzalez A, Nakamura Y, Ikegawa S.
PLoS One. 2010 Mar 18;5(3):e9723.
Genome-wide association study of hematological and biochemical traits in a Japanese population
Kamatani Y, Matsuda K, Okada Y, Kubo M, Hosono N, Daigo Y, Nakamura Y, Kamatani N.
Nature Genetics. 2010 Mar;42(3):210-5.
Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
Matsushita T, Ashikawa K, Yonemoto K, Hirakawa Y, Hata J, Amitani H, Doi Y, Ninomiya T, Kitazono T, Ibayashi S, Iida M, Nakamura Y, Kiyohara Y, Kubo M.
Human Molecular Genetics. 2010 Mar 15;19(6):1137-46.
A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
Ohshige T, Tanaka Y, Araki SI, Babazono T, Toyoda M, Umezono T, Watada H, Suzuki D, Iwamoto Y, Kawamori R, Nakamura Y, Maeda S.
Diabetes Care. 2010 Jan 7.
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
Tomlinson IP, Dunlop M, Campbell H, Zanke B, Gallinger S, Hudson T, Koessler T, Pharoah PD, Niittymäki I, Tuupanen S, Aaltonen LA, Hemminki K, Lindblom A, Försti A, Sieber O, Lipton L, van Wezel T, Morreau H, Wijnen JT, Devilee P, Matsuda K, Nakamura Y, Castellví-Bel S, Ruiz-Ponte C, Castells A, Carracedo A, Ho JW, Sham P, Hofstra RM, Vodicka P, Brenner H, Hampe J, Schafmayer C, Tepel J, Schreiber S, Völzke H, Lerch MM, Schmidt CA, Buch S, Moreno V, Villanueva CM, Peterlongo P, Radice P, Echeverry MM, Velez A, Carvajal-Carmona L, Scott R, Penegar S, Broderick P, Tenesa A, Houlston RS.
Br J Cancer.2010 Jan 19;102(2):447-54. Epub 2009 Nov 17.
2. Papers related to personalized medicine
A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
Yoon KA, Park JH, Han J, Park S, Lee GK, Han JY, Zo JI, Kim J, Lee JE, Takahashi A, Kubo M, Nakamura Y, Lee JS.
Hum Mol Genet. 2010 Dec 15;19(24):4948-54. Epub 2010 Sep 28.
Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Ingle JN, Schaid DJ, Goss PE, Liu M, Mushiroda T, Chapman JA, Kubo M, Jenkins GD, Batzler A, Shepherd L, Pater J, Wang L, Ellis MJ, Stearns V, Rohrer DC, Goetz MP, Pritchard KI, Flockhart DA, Nakamura Y, Weinshilboum RM.
J Clin Oncol. 2010 Nov 1;28(31):4674-82. Epub 2010 Sep 27
Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
Abe H, Ochi H, Maekawa T, Hayes CN, Tsuge M, Miki D, Mitsui F, Hiraga N, Imamura M, Takahashi S, Ohishi W, Arihiro K, Kubo M, Nakamura Y, Chayama K
J Hepatol. 2010 Sep;53(3):439-43. Epub 2010 May 31
Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
Kiyotani K, Mushiroda T, Hosono N, Tsunoda T, Kubo M, Aki F, Okazaki Y, Hirata K, Takatsuka Y, Okazaki M, Ohsumi S,Yamakawa T, Sasa M, Nakamura Y, Zembutsu H
Pharmacogenet Genomics. 2010 Sep;20(9):565-8
Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Akuta N, Suzuki F, Hirakawa M, Kawamura Y, Yatsuji H, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M,Saitoh S, Arase Y, Ikeda K, Chayama K, Nakamura Y, Kumada H
Hepatology. 2010 Aug;52(2):421-9
Development of new HLA-B*3505 genotyping method using Invader assay.
Hosono N, Chantarangsu S, Kiyotani K, Takata S, Tsuchiya Y, Mahasirimongkol S, Chantratita W, Mushiroda T,Nakamura Y, Kubo M
Pharmacogenet Genomics. 2010 Jul 31 [Epub ahead of print]
Inosine Triphosphate Pyrophosphatase Polymorphism Affects Ribavirin-Induced Anemia and Outcomes of Therapy-A Genome-Wide Study of Japanese Hepatitis C Virus Patients.
Ochi H, Maekawa T, Abe H, Hayashida Y, Nakano R, Kubo M, Tsunoda T, Hayes CN, Kumada H, Nakamura Y,Chayama K
Gastroenterology. 2010 Jul 14 [Epub ahead of print]
Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.
Ramamoorthy A, Flockhart DA, Hosono N, Kubo M, Nakamura Y, Skaar TC
Pharmacogenet Genomics. 2010 Jul;20(7):451-4
Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand.
Phasukkijwatana N, Kunhapan B, Stankovich J, Chuenkongkaew WL, Thomson R, Thornton T, Bahlo M, Mushiroda T,Nakamura Y, Mahasirimongkol S, Tun AW, Srisawat C, Limwongse C, Peerapittayamongkol C, Sura T, Suthammarak W, Lertrit P
Hum Genet. 2010 Jul;128(1):39-49. Epub 2010 Apr 21
Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
Kiyotani K, Mushiroda T, Imamura CK, Hosono N, Tsunoda T, Kubo M, Tanigawara Y, Flockhart DA, Desta Z, Skaar TC, Aki F, Hirata K, Takatsuka Y, Okazaki M, Ohsumi S, Yamakawa T, Sasa M, Nakamura Y, Zembutsu H
J Clin Oncol. 2010 Mar 10;28(8):1287-93. Epub 2010 Feb 1
Population-genetic nature of copy number variations in the human genome.
Kato M, Kawaguchi T, Ishikawa S, Umeda T, Nakamichi R, Shapero MH, Jones KW, Nakamura Y, Aburatani H,Tsunoda T
Hum Mol Genet. 2010 Mar 1;19(5):761-73. Epub 2009 Dec 5
A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
Nuinoon M, Makarasara W, Mushiroda T, Setianingsih I, Wahidiyat PA, Sripichai O, Kumasaka N, Takahashi A, Svasti S, Munkongdee T, Mahasirimongkol S, Peerapittayamongkol C, Viprakasit V, Kamatani N, Winichagoon P, Kubo M,Nakamura Y, Fucharoen S.
Hum Genet. 2010 Mar;127(3):303-14
A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
Maeda S, Kobayashi MA, Araki S, Babazono T, Freedman BI, Bostrom MA, Cooke JN, Toyoda M, Umezono T, Tarnow L,Hansen T, Gaede P, Jorsal A, Ng DP, Ikeda M, Yanagimoto T, Tsunoda T, Unoki H, Kawai K, Imanishi M, Suzuki D,Shin HD, Park KS, Kashiwagi A, Iwamoto Y, Kaku K, Kawamori R, Parving HH, Bowden DW, Pedersen O, Nakamura Y
PLoS Genet. 2010 Feb 12;6(2):e1000842
Criterion values for multiplex SNP genotyping by the invader assay.
Nakahara H, Sekiguchi K, Hosono N, Kubo M, Takahashi A, Nakamura Y, Kasai K
Forensic Sci Int Genet. 2010 Feb;4(2):130-6. Epub 2009 Aug 21
Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
Wangsomboonsiri W, Mahasirimongkol S, Chantarangsu S, Kiertiburanakul S, Charoenyingwattana A, Komindr S, Thongnak C, Mushiroda T, Nakamura Y, Chantratita W, Sungkanuparph S.
Clinical Infectious Diseases. 2010 Feb 15;50(4):597-604.
